Blood Urea NitrogenBUN (Blood Urea Nitrogen), BUN:Creatinine Ratio, Urea Nitrogen, Blood ResultsA blood urea nitrogen (BUN) test measures the amount of nitrogen in
your blood that comes from the waste product
urea. NormalNormal values may vary from lab to lab. BUN-to-creatinine ratio| Over 12 months of age:
| 10:1–20:1 |
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| Babies less than 12
months of age: | Up to 30:1 |
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High values- A high BUN value can mean kidney injury or
disease is present. Kidney damage can be caused by
diabetes or
high blood pressure that directly affect the kidneys.
High BUN levels can also be caused by blockage of the urinary tract (by a
kidney stone or tumor) or low blood flow to the
kidneys caused by
dehydration or
heart failure.
- Many medicines may cause a
high BUN. Be sure to tell your doctor about all the nonprescription and
prescription medicines you take.
- A high BUN value may be caused by
a high-protein diet,
Addison's disease, tissue damage (such as from severe
burns), or from bleeding in the gastrointestinal tract.
- High
BUN-to-creatinine ratios occur with sudden (acute) kidney failure, which may be
caused by
shock or severe dehydration. A blockage in the urinary
tract (such as a kidney stone) can cause a high BUN-to-creatinine ratio. A very
high BUN-to-creatinine ratio may be caused by bleeding in the
digestive
tract
or
respiratory tract .
Low values- A low BUN value may be caused by a diet very
low in protein, malnutrition, or severe liver damage.
- Drinking
excessive amounts of liquid may cause overhydration and cause a low BUN
value.
- Women and children may have lower BUN levels than men
because of how their bodies break down protein.
- A low
BUN-to-creatinine ratio may be caused by a diet low in protein, a severe muscle
injury called
rhabdomyolysis, pregnancy,
cirrhosis, or syndrome of inappropriate antidiuretic
hormone secretion (SIADH). SIADH sometimes occurs with lung disease, cancer,
diseases of the central nervous system, and the use of certain
medicines.
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