Treatment Overview
Initial treatment
Treatment of
depression may include antidepressant medication,
professional counseling such as
cognitive-behavioral therapy, or a combination of the
two.
- Professional counseling may be all that you
need for mild to moderate depression.7
- If
your early symptoms are severe, your initial treatment most likely will include
both antidepressants and professional counseling.
- Hospitalization
may be necessary if you show
warning signs of suicide, such as thoughts or plans
about harming yourself or another person, detachment from reality (psychosis), or
excessive use of alcohol or drugs.
Depression can lead to suicide. The warning signs of suicide
change with age.
Depression usually can be successfully treated with medication,
professional counseling, or a combination of the two. However, it sometimes
takes several attempts to find the medication and type of counseling that work
best for you. You may start to feel better within 1 to 3 weeks of taking
antidepressant medicine. But it can take as many as 6 to 8 weeks to see more
improvement. If you have questions or concerns about your medicines, or if you
do not notice any improvement by 3 weeks, talk to your doctor. You and your
health professional will work together to find the right treatment.
If you think you may have depression, take a short quiz to
evaluate your symptoms:
- Interactive Tool: Are You
Depressed?

Should I take medications to treat
depression?
Should I take antidepressants during
pregnancy?
If you have recently given birth, learning how to manage
postpartum depression may help you recover more quickly.
How can I manage postpartum
depression?
In rare cases,
electroconvulsive therapy (ECT) may be an initial
treatment choice for people who cannot take antidepressants, who have not
responded to other treatments, or whose depression is severe and includes
symptoms of
psychosis, suicidal behavior, or an inability to
eat.8 ECT involves an electric stimulation to the head
which causes a brief seizure. This is thought to relieve depression by altering
brain chemicals known as
neurotransmitters.
Ongoing treatment
At least half of those who have one
depression episode will have a recurrence of symptoms
(relapse). Continuing to take antidepressant medicine
after recovery reduces your risk of a relapse.9 Taking
your medicine for at least 6 months after you feel better can help keep you
from getting depressed again. If this is not the first time you have been
depressed, your doctor may want you to take these medicines even longer.
Ongoing treatment for depression also includes:
- Eating a balanced diet.
- Avoiding
alcohol.
- Getting exercise.
- Getting quality
sleep.
It may also be helpful for you to obtain social support from
family and friends.
If you have another illness along with depression, you need to
continue treatment for your other illness. It is possible for other mood
disorders such as
anxiety and anxiety disorders,
psychosis, or
mania to accompany depression. For more information,
see the topics
Generalized Anxiety Disorder,
Social Anxiety Disorder, and
Bipolar Disorder.
Treatment if the condition gets worse
If your
depression gets worse while you are receiving
professional counseling alone, medication can be added to your treatment.
- Evidence shows that adding medications to
counseling for severe depression works better than counseling alone.9
- If you have recurrent depression, you may need
to take antidepressant medications for the rest of your life.
If your depression gets worse while you are already taking
medications and receiving professional counseling, different or additional
medications may be tried.
Electroconvulsive therapy (ECT) has been shown to be
an effective treatment for severe depression or depression that has not been
helped by other treatment.9, 8
ECT involves an electric stimulation to the head that causes a brief seizure.
This is thought to relieve depression by altering brain chemicals known as
neurotransmitters. ECT will need to be followed with
medications and counseling, because
relapse of symptoms is common.10
If your symptoms of depression get worse, it is essential to
work with your health professional to find effective treatment. Major
depression may be a risk factor for developing heart problems such as
coronary artery disease or
heart attack.11 However, the
greatest danger from depression is
suicide. Up to 15% of people with depression die by
suicide.3
The warning signs of suicide change with age.
What To Think About
FDA Advisories. The U.S. Food and Drug
Administration (FDA) has issued:
- An
advisory on antidepressant medicines and the risk of
suicide. The FDA does not recommend that people stop using these medicines.
Instead, a person taking antidepressants should be watched for
warning signs of suicide. This is especially important
at the beginning of treatment or when doses are changed. The FDA also advises
that patients be observed for increases in anxiety, panic attacks, agitation,
irritability, insomnia, impulsivity, hostility, and mania.
- A
warning about the antidepressants Paxil and Paxil CR
and birth defects. Taking these medicines in the first 12 weeks of pregnancy
may increase your chance of having a baby with a birth defect.
Should I take antidepressants during
pregnancy?
Anyone can develop depression regardless of age, race, or social
status. As many as 1 out of every 10 people who visit a doctor has depression,
but it goes unrecognized or undertreated in about half of those cases.2 If left untreated, depression can lead to poor quality of
life and higher risk of suicide.
Less than one-third of people with depression seek professional
treatment.12 Even when treatment is sought, health
professionals sometimes attribute the vague symptoms of depression to other
illnesses. You may not realize you are depressed, or you may be embarrassed to
seek treatment. However, it is important to seek treatment as soon as you
suspect that you or someone you love is depressed. The sooner you seek
treatment, the better your chance for a quick and full recovery. Preventing
recurrence of depression is also important.
If you need help deciding whether to see your doctor, see
some
reasons why people don't get help and how to overcome them.
Depression is not normal at any age, and treatment is important.
- Depression is often underdiagnosed in
children and older adults. In children and adolescents, depression might be
mistaken for hormonal "moodiness." For more information, see
Depression in Children and Teens.
- Older
adults may think it is normal to experience feelings of depression along with
aging. Early treatment of depression in older adults can delay nursing home
placement. The risk of death associated with depression increases significantly
during the first year an older adult enters a nursing home.3
Family involvement and support in the treatment of depression can
be very important, especially for children, teens, and older adults. Sometimes
parents of depressed children and teens may also be diagnosed with depression
and need treatment. Sometimes one or both parents can be depressed first and
this can lead to their children also being diagnosed with depression.
If you have recently given birth, learning how to manage
postpartum depression early on may help you recover more quickly and prevent a
prolonged or serious problem with postpartum depression.
How can I manage postpartum
depression?