Conditions other than coronary artery disease and heart attack that cause chest pain

While chest pain is typical of a heart attack and coronary artery disease, it may also be caused by:

· Digestive system problems.

  • Stomach acid moving upward into the esophagus (esophageal reflux or heartburn)
  • Muscle spasm of the esophagus
  • Gallbladder disease
  • A sore in the lining of the stomach or small intestine (peptic ulcer)

· Inflammation.

  • Inflammation of the membrane surrounding the lungs (pleurisy)
  • Inflammation of the membrane covering the heart (pericarditis)

· Heart, lung, and heart valve problems.

  • A tear in the wall of the aorta (aortic dissection)
  • Narrowing of the aortic valve (aortic stenosis)
  • A blood clot in one of the arteries of the lungs (pulmonary embolism)

· Other causes.

  • Panic, anxiety, stress, or depression
  • Shingles (herpes zoster), a reactivation of the chickenpox virus that causes pain and a rash
  • Pain in the bones and/or muscles of the chest wall


Author: Robin Parks, MSLast Updated: May 14, 2007
Medical Review: Caroline S. Rhoads, MD - Internal Medicine
Stephen Fort, MD, MRCP, FRCPC - Interventional Cardiology

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