A decrease in the number of circulating blood cells (anemia) is a common problem in people who have
chronic kidney disease. It is often caused by a
decrease in the amount of a protein produced by the kidneys (erythropoietin).
Some people who receive man-made erythropoietin (rhEPO therapy)
continue to have anemia because of low levels of iron in their blood. These
people are usually given extra iron to help treat this problem. Intravenous
(IV) iron may be needed if oral iron does not increase iron levels. IV iron can
also be used to treat anemia that occurs during
hemodialysis.1